Polynucleotides Skin Regeneration Treatment
Polynucleotides (PN) are advanced regenerative molecules used in aesthetic medicine to support skin repair, hydration, and collagen stimulation. These highly purified DNA fragments are biocompatible and work by activating the skin’s natural healing and regeneration processes at a cellular level.
Polynucleotides help restore the skin’s structure from within by improving tissue quality, strengthening the skin barrier, and stimulating fibroblast activity responsible for collagen and elastin production.
This treatment focuses on skin quality restoration, making it ideal for patients seeking natural-looking rejuvenation.
How Polynucleotides Work
Polynucleotides support skin regeneration by:
• Stimulating fibroblast activity
• Encouraging collagen production
• Improving microcirculation
• Providing deep hydration support
• Reducing inflammation and supporting tissue repair
Because the treatment activates the body’s own regenerative mechanisms, improvements appear progressively and naturally over time.
Treatment Areas
Polynucleotides can be safely used on delicate and regenerative-challenging areas, including:
• Face
• Under-eye area
• Neck
• Décolletage
• Acne-scarred skin
Treatment Course
For best results, polynucleotide treatments are typically performed as a course:
Initial course:
3–4 sessions spaced 3–4 weeks apart.
Maintenance:
Every 6–12 months, depending on skin condition and goals.
The treatment is performed using microinjections into the dermis, with minimal downtime. Mild swelling or small injection marks may appear temporarily and usually settle within a few days.